Synthesis of an electronically-tuned minimally interfering alkynyl photo-affinity label to measure small molecule–protein interactions
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DOI: 10.1016/j.tet.2018.03.024
Abstract: Abstract We report the synthesis of an electronically-tuned minimally interfering photo-affinity label (MI-PAL), a compact five-carbon tag functionalized with an alkyl diazirine and alkyne handle. MI-PAL is compatible with protein photo-conjugation, click chemistry and mass… read more here.
Keywords: minimally interfering; photo; synthesis electronically; tuned minimally ... See more keywords