A new and efficient enantioselective synthesis of both enantiomers of the calcium channel blocker bepridil
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DOI: 10.1039/c6nj02928k
Abstract: A concise and efficient enantioselective synthesis of both enantiomers of bepridil, a calcium channel blocker, is reported. Jacobsen's hydrolytic kinetic resolution method was utilized to resolve racemic 2-(isobutoxymethyl)oxirane. The incorporation of the succinimide moiety by… read more here.
Keywords: efficient enantioselective; calcium channel; channel blocker; synthesis enantiomers ... See more keywords