Computational mechanistic study on Pd-catalyzed stereoselective synthesis of Z-1,3- and E-1,4-enynes from ligand-controlled regiodivergent hydroalkynylations of allenamides
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DOI: 10.1016/j.mcat.2020.110765
Abstract: Abstract Density functional theory (DFT) calculations show that regardless of using BrettPhos or (o-OMePh)3P ligand, the Pd-catalyzed synthesis of both 1,3- and 1,4-enynes from hydroalkynylations of allenamides proceeds through the hydropalladation mechanism, rather than the… read more here.
Keywords: computational mechanistic; mechanistic study; synthesis enynes; hydroalkynylations allenamides ... See more keywords
Highly Selective Synthesis of 1,3-Enynes, Pyrroles, and Furans by Manganese(I)-Catalyzed C–H Activation
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DOI: 10.1021/acscatal.9b03965
Abstract: A highly selective Mn(I)-catalyzed alkenylation of arenes and heteroarenes with 1,3-diynes is described. The reported transformation overcomes regio-, chemo-, and stereoselectivity challenges assoc... read more here.
Keywords: synthesis enynes; highly selective; furans manganese; selective synthesis ... See more keywords
In situ generation of highly reactive allenes from nitrocyclopropanes: controllable synthesis of enynes and enesters.
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DOI: 10.1039/d1cc01573g
Abstract: A new and efficient strategy for ring-opening reactions of nitrocyclopropanes is developed for the first time for the divergent synthesis of enynes and enesters via in situ generated highly reactive electron-deficient intermediate allenes. Controllable approaches… read more here.
Keywords: synthesis enynes; highly reactive; situ generation; enynes enesters ... See more keywords
Synthesis of 1,4-enynes via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc05221g
Abstract: Synthesis of 1,4-enynes was performed via nickel-catalyzed cross-coupling of allylic alcohols with alkynylzinc reagents. The reaction features high regio- and E/Z-selectivity when aryl-substituted allylic alcohols were employed. The method also exhibits a wide scope of… read more here.
Keywords: synthesis enynes; allylic alcohols; cross coupling; catalyzed cross ... See more keywords