Concise synthesis of 1-epi-castanospermine
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2017.05.013
Abstract: Abstract 1-epi-Castanospermine (5) was synthesized from readily available 2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin (11) in 9 steps and 21% overall yield, with selective debenzylation, Barbier reaction and reductive amination as the main reaction steps. read more here.
Keywords: concise synthesis; synthesis epi; castanospermine; epi castanospermine ... See more keywords
Total synthesis of 4-epi-atpenin A5 as a potent nematode complex II inhibitor
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.02.050
Abstract: Abstract It is clear that atpenins and their analogs are useful chemical tools for elucidation of complex II functionality and that they could act as lead compounds for the development of novel helminth complex II-specific… read more here.
Keywords: synthesis epi; total synthesis; synthesis; epi atpenin ... See more keywords
Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2- epi-Narciclasine.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.8b00218
Abstract: An efficient protocol for the isolation of narciclasine from common Amaryllidaceae bulbs, separation from haemanthamine, and the occurrence of a trace alkaloid, 2- epi-narciclasine, are reported. Attempts to convert natural narciclasine to its C-2 epimer… read more here.
Keywords: synthesis epi; epi narciclasine; narcissus galanthus; isolation ... See more keywords
Synthesis of 3-epi-Hypatulin B Featuring a Late-Stage Photo-Oxidation in Flow.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00689
Abstract: A synthesis of 3-epi-hypatulin B, a highly oxygenated and densely functionalized bicyclic scaffold, is reported. The carbon skeleton was prepared by functionalization of a cyclopentanone and an intramolecular Mukaiyama aldol reaction. Highlights include a late-stage… read more here.
Keywords: epi hypatulin; synthesis; flow; late stage ... See more keywords
Rapid Synthesis of the epi-Biotin Sulfone via Tandem S,N-Carbonyl Migration/aza-Michael/Spirocyclization and Haller–Bauer Reaction
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01030
Abstract: A synthesis of 2-epi-biotin sulfone was accomplished from commercially available l-cysteine. The synthesis features an unprecedented tandem S,N-carbonyl migration/aza-Michael/spirocyclization reaction from an l-cysteine-derived enone with aq. ammonia, in which three new sigma bonds and two… read more here.
Keywords: epi biotin; reaction; synthesis; sulfone ... See more keywords
An Enantiospecific Synthesis of 5-epi-α-Bulnesene
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28093900
Abstract: As a result of its unique fragrance and wider role in traditional medicine, agarwood produced in Aquilaria spp. and certain other trees has been harvested to near extinction as a natural phenomenon. Artificially induced agarwood… read more here.
Keywords: synthesis; enantiospecific synthesis; epi bulnesene; synthesis epi ... See more keywords