Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc03399d
Abstract: BAG3 protein has emerged as a key regulator of important cellular processes and its expression is increased in some tumor types; however, despite its potential value for future chemotherapeutics, no selective BAG3 modulators have been… read more here.
Keywords: first selective; discovery synthesis; bag3; synthesis first ... See more keywords
A synthesis of the first full-scale experiment in Central America
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pavement Engineering"
DOI: 10.1080/10298436.2019.1628959
Abstract: ABSTRACT The initial full-scale experiment in Costa Rica began in 2012 under a program that has been identified as PaveLab. The main purposes were to identify the effect of typical construction practices in the country:… read more here.
Keywords: synthesis first; first full; full scale; scale experiment ... See more keywords