Synthesis of Fluorinated Dialkyl Carbonates from Carbon Dioxide as a Carbonyl Source.
Sign Up to like & getrecommendations! Published in 2020 at "ChemSusChem"
DOI: 10.1002/cssc.202000090
Abstract: Fluorinated dialkyl carbonates, which serve as environmentally benign phosgene substitutes, were successfully produced from carbon dioxide either directly or indirectly. Nucleophilic addition of 2,2,2-trifluoroethanol to carbon dioxide and subsequent reaction with 2,2,2-trifluoroethyltriflate ( E OTf… read more here.
Keywords: dioxide carbonyl; fluorinated dialkyl; dialkyl carbonates; carbon dioxide ... See more keywords
Synthesis of Fluorinated Leishmania Cap Trisaccharides for Diagnostic Tool and Vaccine Development
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201800384
Abstract: Bearing in mind the often insufficient metabolic stability of carbohydrate antigens, which impairs both the bioavailability and immunogenicity of a given hapten, the development of chemically modified analogs with improved antigenicity is an important step… read more here.
Keywords: leishmania cap; trisaccharides diagnostic; cap trisaccharides; synthesis fluorinated ... See more keywords
Synthesis of a Fluorinated Derivative of Sigma-1 Receptor Modulator E1R: 2-[5-oxo-3-phenyl-2-(trifluoromethyl)pyrrolidin-1-yl]Acetamide
Sign Up to like & getrecommendations! Published in 2020 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-020-02814-1
Abstract: The ozonation of N-Boc-protected 3-methylidene-4-phenyl-5-(trifluoromethyl)pyrrolidin-2-one resulted in its transformation into 3-hydroxy-4-phenyl-5-(trifluoromethyl)-3-pyrrolin-2-one. Catalytic hydrogenation of its O-Boc-protected derivative introduced a way to reduce the double bond in combination with elimination of the hydroxy group leading to… read more here.
Keywords: phenyl trifluoromethyl; trifluoromethyl pyrrolidin; phenyl; synthesis fluorinated ... See more keywords
Facile synthesis of fluorinated resorcinol-formaldehyde aerogels
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2016.11.001
Abstract: In this paper, we have tried to use some unconventional solvents for the preparation of resorcinol-formaldehyde (RF) aerogels. The nature of the gelation solvent is found to greatly influence the properties of RF aerogels, e.g.,… read more here.
Keywords: facile synthesis; formaldehyde aerogels; resorcinol formaldehyde; synthesis fluorinated ... See more keywords
Synthesis of α-Fluorinated Areneacetates through Photoredox/Copper Dual Catalysis.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00969
Abstract: The development of mild and practical conditions for the fluoroalkylation of arenes is an ongoing challenge in chemical organic synthesis. Herein, we report a metallaphotoredox method for the preparation of fluoroalkyl arenes based on the… read more here.
Keywords: catalysis; synthesis fluorinated; dual catalysis; copper dual ... See more keywords
Enantioselective Synthesis of Fluorinated Indolizidinone Derivatives
Sign Up to like & getrecommendations! Published in 2023 at "Organic Letters"
DOI: 10.1021/acs.orglett.3c00903
Abstract: The enantioselective synthesis of fluorinated indolizidinone derivatives has been developed. The process involved an enantioselective intramolecular aza-Michael reaction of conjugated amides bearing a pendant α,β-unsaturated ketone moiety, catalyzed by the (S)-TRIP-derived phosphoric acid, followed by… read more here.
Keywords: enantioselective synthesis; synthesis fluorinated; fluorinated indolizidinone; indolizidinone derivatives ... See more keywords
Synthesis of α-Fluorinated Imides via Direct Fluorohydroxylation of Ynamides.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b01428
Abstract: A practical synthesis of α-fluorinated imides via the catalyst-free fluorohydroxylation of ynamides is developed. The reaction employs commercially available Selectfluor (F-TEDA-BF4) and H2O as the fluorine and hydroxyl sources, respectively. A broad range of aryl-… read more here.
Keywords: synthesis fluorinated; fluorohydroxylation ynamides; via direct; fluorinated imides ... See more keywords
Synthesis of Fluorinated Hydrazinylthiazole Derivatives: A Virtual and Experimental Approach to Diabetes Management
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c00265
Abstract: A novel series of fluorophenyl-based thiazoles was synthesized following the Hanztsch method. All of the compounds were initially verified with physical parameters (color, melting point, retardation factor (Rf)), which were further confirmed by several spectroscopic… read more here.
Keywords: hydrazinylthiazole derivatives; fluorinated hydrazinylthiazole; derivatives virtual; synthesis fluorinated ... See more keywords