Synthesis of 2-fluoro-substituted and 2,6-modified purine 2',3'-dideoxy-2',3'-difluoro-d-arabinofuranosyl nucleosides from d-xylose.
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.02.027
Abstract: A series of novel purine-modified 2',3'-dideoxy-2',3'-difluro-D-arabinonucleosides, including fluorinated analogs of fludarabine and nelarabine, have been prepared via anion glycosylation reactions of salts of 2-fluoropurine derivatives with the glycosyl bromide. A short and efficient synthetic route… read more here.
Keywords: difluoro; synthesis fluoro; difluoro arabinofuranosyl; purine ... See more keywords
Design and Synthesis of Fluoro Analogues of Vitamin D
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DOI: 10.3390/ijms22158191
Abstract: The discovery of a large variety of functions of vitamin D3 and its metabolites has led to the design and synthesis of a vast amount of vitamin D3 analogues in order to increase the potency… read more here.
Keywords: design synthesis; vitamin analogues; synthesis fluoro; fluoro analogues ... See more keywords