Rapid and scalable synthesis of fluoroketones via cerium-mediated C-C bond cleavage.
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DOI: 10.1039/d0cc08183c
Abstract: Ketones with remote fluorination are an important motif in the synthesis of bioactive molecules. Here we demonstrate that ceric ammonium nitrate (CAN) is able to produce this functionality under incredibly mild conditions and short reaction… read more here.
Keywords: via cerium; rapid scalable; fluoroketones via; synthesis fluoroketones ... See more keywords