Palladium-Catalyzed Multicomponent Synthesis of Fully Substituted Alkylidene Furanones.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02578
Abstract: In the presence of a catalytic amount of Pd(OAc)2 and XantPhos, the three-component reaction of ynones, imines, and aryl iodides affords fully substituted alkylidene-furan-3(2H)-ones via a sequence of the Mannich reaction followed by chemo- and… read more here.
Keywords: fully substituted; multicomponent synthesis; synthesis fully; palladium catalyzed ... See more keywords
Regioselective Synthesis of Fully Substituted Fused Pyrroles through an Oxidant-Free Multicomponent Reaction.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03889
Abstract: The synthesis of fully substituted fused pyrroles through a multicomponent reaction between a thioamide, an aldehyde, and ammonium acetate is described. This process improves on a route commonly employed in the patent literature by avoiding… read more here.
Keywords: fused pyrroles; multicomponent reaction; substituted fused; reaction ... See more keywords
Synthesis of Fully Biobased Polyesters from Plant Oil
Sign Up to like & getrecommendations! Published in 2017 at "ACS Sustainable Chemistry & Engineering"
DOI: 10.1021/acssuschemeng.7b01668
Abstract: Self-metathesis of fatty acid methyl esters (FAMEs) from natural oils and commercial oleic acid was carried out using a microwave reactor in solvent-free conditions. Self-metathesis products were further identified and quantified by gas chromatography–mass spectroscopy… read more here.
Keywords: plant oil; polyesters plant; fully biobased; synthesis fully ... See more keywords
Stereocontrolled Synthesis of the Fully Glycosylated Monomeric Unit of Lomaiviticin A.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c07631
Abstract: We describe a stereocontrolled synthesis of 3, the fully glycosylated monomeric unit of the dimeric cytotoxic bacterial metabolite (-)-lomaiviticin A (2). A novel strategy involving convergent, site- and stereoselective coupling of the β,γ-unsaturated ketone 6… read more here.
Keywords: glycosylated monomeric; stereocontrolled synthesis; synthesis; fully glycosylated ... See more keywords
Synthesis of fully arylated (hetero)arenes.
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DOI: 10.1039/c6cc09550j
Abstract: Multiply arylated arenes are privileged structures with highly useful functions and fascinating optoelectronic and biological properties. This feature article reports the synthesis of fully arylated (hetero)arenes bearing more than two different aryl substituents and categorizes… read more here.
Keywords: arylated hetero; synthesis fully; hetero arenes; hetero ... See more keywords
DBU-mediated [4 + 2] annulations of donor–acceptor cyclopropanes with 3-aryl-2-cyanoacrylates for the synthesis of fully substituted anilines
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra07230a
Abstract: A facile synthesis of fully substituted anilines by the DBU-mediated [4 + 2] annulation of donor–acceptor 1,1-dicyano-cyclopropanes with 3-aryl-2-cyanoacrylate has been developed. This reaction involves a highly efficient multiple domino sequence consisting of ring opening… read more here.
Keywords: substituted anilines; fully substituted; synthesis fully; donor acceptor ... See more keywords
Stereoselective synthesis of fully substituted ethylenes via an Ag-catalyzed 1,6-nucleophilic addition/annulation cascade.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc10022a
Abstract: A catalytic 1,6-nucleophilic addition/annulation cascade was developed for the first time, and used to produce 27 hitherto unreported ethylene-linked 1-naphthol-imidazole pairs with generally good yields and complete stereoselectivity. An Ag2O-catalyzed reaction of yne-allenone esters with… read more here.
Keywords: fully substituted; annulation cascade; addition; synthesis fully ... See more keywords
Domino synthesis of fully substituted pyridines by silver-catalyzed chemoselective hetero-dimerization of isocyanides
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DOI: 10.1039/c9qo01333d
Abstract: A silver-catalyzed hetero-dimerization of various vinyl isocyanides with isocyanoacetamides has been developed. This multistep domino reaction provides a facile protocol for the expedient synthesis of fully substituted pyridines in a single operation from readily available… read more here.
Keywords: silver catalyzed; fully substituted; substituted pyridines; synthesis fully ... See more keywords
Zinc-catalyzed multicomponent reactions: Facile synthesis of fully substituted pyridines
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1463545
Abstract: Abstract A first example of environmentally benign zinc complex catalyzed one-pot four-component reaction between malononitrile, ketone, ammonium acetate and aromatic aldehyde for the facile synthesis of fully substituted pyridines just within 2 min in environmentally friendly… read more here.
Keywords: fully substituted; substituted pyridines; facile synthesis; synthesis fully ... See more keywords