Synthesis of Functionalized δ‐Hydroxy‐β‐keto Esters and Evaluation of Their Anti‐inflammatory Properties
Sign Up to like & getrecommendations! Published in 2022 at "Chembiochem"
DOI: 10.1002/cbic.202200073
Abstract: δ‐Hydroxy‐β‐keto esters and δ,β‐dihydroxy esters are characteristic structural motifs of statin‐type natural products and drug candidates. Here, we describe the synthesis of functionalized δ‐hydroxy‐β‐keto esters in good yields and excellent enantioselectivities using Chan's diene and… read more here.
Keywords: synthesis functionalized; functionalized hydroxy; hydroxy keto; keto esters ... See more keywords
2D‐2D Nanocomposite of MoS2‐Graphitic Carbon Nitride as Multifunctional Catalyst for Sustainable Synthesis of C3‐Functionalized Indoles
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DOI: 10.1002/cctc.201800369
Abstract: A nanocomposite of two‐dimensional MoS2 supported on graphitic C3N4 nanosheets has been prepared by a facile ultrasonication method followed by demonstrating its ability to catalyze the synthesis of several indole derivatives. The as‐prepared nanocomposite catalyst… read more here.
Keywords: functionalized indoles; synthesis functionalized; nanocomposite mos2; catalyst ... See more keywords
Synthesis of Functionalized Quinolines from 4-(o-Nitroaryl)-Substituted 3-Acyl-4,5-Dihydrofurans: Reductive Cyclization and C=C Bond Cleavage
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DOI: 10.1002/ejoc.201700256
Abstract: A new synthetic approach to functionalized quinolines was developed based on the application of Zn–AcOH system as a simple and efficient reductive agent towards 4-(o-nitroaryl)-3-acyl-substituted 4,5-dihydrofurans. Reduction of 3-carbonyl-substituted dihydrofurans is accomplished by C=C double-bond… read more here.
Keywords: synthesis functionalized; functionalized quinolines; cyclization; bond cleavage ... See more keywords
An Efficient and Facile Synthesis of Functionalized Indole-3-yl Pyrazole Derivatives Starting from 3-Cyanoacetylindole
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DOI: 10.1002/jhet.2654
Abstract: The versatile hitherto reported 3-(1H-indol-3-yl)-1H-pyrazol-5-amine () was synthesized by the reaction of 3-cyanoacetylindole () with hydrazine hydrate in refluxing ethanol and used as a key intermediate for the synthesis of novel pyrazolo[1,5-a]pyrimidines via its reactions… read more here.
Keywords: pyrazole; synthesis functionalized; facile synthesis; functionalized indole ... See more keywords
ONE-POT DIASTEREOSELECTIVE SYNTHESIS OF FUNCTIONALIZED 4,5-DIHYDROPYRROLES BY REACTIONS OF ARYLGLYOXALS, β-DICARBONYL COMPOUNDS, AND AROMATIC AMINES
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/5055
Abstract: A multicomponent reaction of arylglyoxal hydrates, acetylacetone or acetoacetic ester, aniline or its 3(4)-substituted analogs in 1:1:2 ratio occurred upon stirring in methanol, giving 4-arylamino-5-hydroxypyrroline derivatives containing 4,5-dihydroxypyrrolines as impurities. read more here.
Keywords: diastereoselective synthesis; synthesis functionalized; functionalized dihydropyrroles; dihydropyrroles reactions ... See more keywords
SYNTHESIS OF FUNCTIONALIZED OXAZOLIDINES BY MULTICOMPONENT REACTIONS OF 1,2-AMINO ALCOHOLS
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DOI: 10.1007/5439
Abstract: Recent (2011–2019) multicomponent syntheses of functionalized oxazolidines using 1,2-amino alcohols as starting materials are reviewed. The synthetic strategies are gathered into three groups: metal-free domino annulation/Mannich reactions, transition metal-catalyzed cascade reactions, extended one-pot asymmetric azaelectrocyclization. read more here.
Keywords: multicomponent reactions; functionalized oxazolidines; synthesis functionalized; reactions amino ... See more keywords
Simple and efficient route for the synthesis of functionalized 2,3,7,8-tetrahydro-4H,6H-pyrano[3,2-g]chromene-4,6-diones
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DOI: 10.1007/s10593-017-2085-x
Abstract: A novel series of spiro[chromene-2,1'-cyclohexan]-4(3H)-one derivatives containing either a chalcone or flavanone fragment in their molecules was synthesized. 2'-Hydroxychalcones, containing a spirochromanone moiety, underwent cyclocondensation with formation of a condensed pyran ring. The catalytic efficiency… read more here.
Keywords: route synthesis; chromene; synthesis functionalized; efficient route ... See more keywords
Synthesis of functionalized triazolo[1,5-a]pyrimidine derivatives
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DOI: 10.1007/s10593-018-2230-1
Abstract: New triazolo[1,5-a]pyrimidines containing aroyl and acetyl or ester groups in the pyrimidine ring were synthesized in a process related to the Biginelli-like reaction, using hydrates of arylglyoxals, β-dicarbonyl compounds, and 1H-1,2,4-triazol-5-amine. Reaction was carried out… read more here.
Keywords: triazolo pyrimidine; synthesis functionalized; chemistry; pyrimidine derivatives ... See more keywords
Facile synthesis of β-functionalized “push-pull” Zn(II) porphyrins for DSSC applications
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DOI: 10.1016/j.dyepig.2017.07.053
Abstract: Abstract Three new β -substituted “push-pull” Zn(II) porphyrin dyes with various electron donors at meso- positions and cyanoacetic acid as acceptor at β -position have been designed and synthesized. These porphyrins have been characterized by… read more here.
Keywords: synthesis functionalized; facile synthesis; push; push pull ... See more keywords
Nickel-Catalyzed Carbonylative Synthesis of Functionalized Alkyl Iodides
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DOI: 10.1016/j.isci.2018.09.024
Abstract: Summary Functionalized alkyl iodides are important compounds in organic chemistry and biology. In this communication, we developed an interesting nickel-catalyzed carbonylative synthesis of functionalized alkyl iodides from aryl iodides and ethers. With Mo(CO)6 as the… read more here.
Keywords: alkyl iodides; synthesis functionalized; nickel catalyzed; functionalized alkyl ... See more keywords
Corrigendum to “One-pot synthesis of functionalized mesoporous fibrous silica nanospheres for dye adsorption: Isotherm, kinetic, and thermodynamic studies” [J. Mol. Liq. 300 (2020) 112367]
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2020.113063
Abstract: Abstract In this corrigendum, we present corrections to our published article “One-pot synthesis of functionalized mesoporous fibrous silica nanospheres for dye adsorption: isotherm, kinetic, and thermodynamic studies” [J. Mol. Liquids 300 (2020) 112367]. Corrections include… read more here.
Keywords: mesoporous fibrous; synthesis functionalized; fibrous silica; pot synthesis ... See more keywords