Design and synthesis of fungal-selective resorcylate aminopyrazole Hsp90 inhibitors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.9b00826
Abstract: The molecular chaperone Hsp90, essential in all eukaryotes, plays a multifaceted role in promoting survival, virulence and drug resistance across diverse pathogenic fungal species. The chaperone is also critically important, however, to the pathogen's human… read more here.
Keywords: design synthesis; fungal selective; hsp90; hsp90 inhibitors ... See more keywords
Biocatalytic synthesis of fungal β-glucans
Sign Up to like & getrecommendations! Published in 2018 at "Catalysts"
DOI: 10.3390/catal8070274
Abstract: Glucans are the dominant polysaccharide constituents of fungal cell walls. Remarkably, these major bioactive polysaccharides account for the beneficial effects that have been observed by many mushr ... read more here.
Keywords: biocatalytic synthesis; synthesis fungal; fungal glucans;