Gold(I)-Catalyzed Cycloisomerization-Indole Addition Cascade: Synthesis of 3(2H)-Furanone-Incorporated Unsymmetrical 3,3'- Bis(indolyl)methanes.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01845
Abstract: An unprecedented Au(I)-catalyzed domino intramolecular carbonyl-alkyne cyclization/indole addition strategy has been disclosed here. This generalized strategy enables the synthesis of 3(2H)-furanone-incorporated unsymmetrical bis(indolyl)methanes with generation of a stereocenter at the furanone junction from easily accessible… read more here.
Keywords: addition; synthesis; synthesis furanone; indolyl ... See more keywords