Reinvestigation of synthesis of halo-substituted 3-phenyl-1-(2-pyridyl)-2-propen-1-ones (azachalcones). A tandem reaction for formation of penta-substituted cyclohexanols
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DOI: 10.1016/j.tet.2017.06.033
Abstract: Abstract A systematic study of the synthesis of halo-substituted azachalcones was conducted. During the reaction course, we obtained not only the target azachalcones, but also penta-substituted cyclohexanols, which are seldom reported in the literatures. The… read more here.
Keywords: halo substituted; substituted cyclohexanols; formation; reaction ... See more keywords
Direct synthesis of 3-halo-3-arylacrylonitriles from the addition of cyanoalkynes with alkaline metal halides
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DOI: 10.1016/j.tetlet.2017.07.104
Abstract: Abstract An efficient synthesis of 3-halo-3-arylacrylonitrile is described from the direct addition between cyanoalkynes and inorganic alkaline metal halides such as LiCl, LiBr and KI in good to satisfactory yields. No transition metal is needed… read more here.
Keywords: synthesis; addition cyanoalkynes; metal; alkaline metal ... See more keywords
Synthesis of 6-Halo-Substituted Pericosine A and an Evaluation of Their Antitumor and Antiglycosidase Activities
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DOI: 10.3390/md20070438
Abstract: The enantiomers of 6-fluoro-, 6-bromo-, and 6-iodopericosine A were synthesized. An efficient synthesis of both enantiomers of pericoxide via 6-bromopericosine A was also developed. These 6-halo-substituted pericosine A derivatives were evaluated in terms of their… read more here.
Keywords: substituted pericosine; antitumor; pericosine evaluation; halo substituted ... See more keywords