Synthesis and Hydrolytic Stability of N- and O-Methyloxyamine Linkers for the Synthesis of Glycoconjugates
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DOI: 10.1002/ejoc.201601534
Abstract: A direct comparison of N- vs. O-methyloxyamine linkers for carbohydrates is presented, include optimised synthetic routes, glycan conjugations and studies into hydrolytic stabilities. From this work we demonstrate that pH, glycan concentration and buffer strength… read more here.
Keywords: methyloxyamine linkers; stability methyloxyamine; linkers synthesis; hydrolytic stability ... See more keywords