Microwave-assisted synthesis of hydroxymethyl ketones using azolium-2-carboxylate zwitterions as catalyst precursors
Sign Up to like & getrecommendations! Published in 2017 at "Tetrahedron"
DOI: 10.1016/j.tet.2017.11.024
Abstract: Abstract Following an initial screening of six common imidazolium, imidazolinium, and dithiolium salts in the presence of a base, 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IDip) and 1,3-dimesitylimidazolin-2-ylidene (SIMes) were identified as promising organocatalysts for the microwave-assisted synthesis of hydroxymethyl… read more here.
Keywords: hydroxymethyl ketones; carboxylate zwitterions; microwave assisted; azolium carboxylate ... See more keywords
Stereoselective synthesis of 4-hydroxymethyl-1,3-oxazolidin-2-one derivatives from novel 2-hydroxymethylaziridines
Sign Up to like & getrecommendations! Published in 2018 at "Synthetic Communications"
DOI: 10.1080/00397911.2018.1490771
Abstract: Abstract A stereoselective and simple method for the synthesis of trans-2-hydroxymethyl-N-alkyl-1,3-oxazolidin-2-ones is described. The synthesis involved the reduction of trans-aziridine-2-carboxylates with LiAlH4, followed by a ring opening and a cyclization reaction in the presence of… read more here.
Keywords: one derivatives; stereoselective synthesis; oxazolidin one; hydroxymethyl oxazolidin ... See more keywords