Efficient Synthesis of Hydroxytyrosol from l-3,4-Dihydroxyphenylalanine Using Engineered Escherichia coli Whole Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b01856
Abstract: Hydroxytyrosol is a high-value-added compound with a variety of biological and pharmacological activities. In this study, a whole-cell catalytic method for the synthesis of hydroxytyrosol was developed: aromatic amino acid aminotransferase (TyrB), l-glutamate dehydrogenase (GDH),… read more here.
Keywords: escherichia coli; synthesis hydroxytyrosol; hydroxytyrosol dihydroxyphenylalanine; hydroxytyrosol ... See more keywords
Multienzyme cascade for synthesis of hydroxytyrosol via engineered Escherichia coli
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-024-84624-5
Abstract: Hydroxytyrosol, a fine chemical, is widely utilized in food and pharmaceutical industries. In this study, we constructed a pathway to produce hydroxytyrosol by co-expressing tyrosin-phenol lyase (TPL), L-amino acid dehydrogenase (aadL), α-keto acid decarboxylase (KAD),… read more here.
Keywords: hydroxytyrosol; hydroxytyrosol via; cascade synthesis; synthesis hydroxytyrosol ... See more keywords