Synthesis and immunological studies of β-1,2-mannan-peptide conjugates as antifungal vaccines.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2019.04.001
Abstract: Fungal cell surface carbohydrates and proteins are useful antigens for the development of antifungal vaccines. In this study, glycopeptides consisting of the β-1,2-mannan and N-terminal peptide epitopes of Candida albicans (C. albicans) cell wall phosphomannan complex… read more here.
Keywords: synthesis immunological; mannan peptide; studies mannan; antifungal vaccines ... See more keywords
Synthesis and immunological studies of group AStreptococcuscell-wall oligosaccharide–streptococcal C5a peptidase conjugates as bivalent vaccines
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DOI: 10.1039/c9qo00651f
Abstract: A convergent synthesis of GAS cell-wall oligosaccharides and their efficient conjugation with the ScpA193 carrier protein to generate glycoconjugates as potential bivalent vaccines were reported. read more here.
Keywords: synthesis immunological; studies group; astreptococcuscell wall; immunological studies ... See more keywords
Synthesis and Immunological Evaluation of Mannosylated Desmuramyl Dipeptides Modified by Lipophilic Triazole Substituents
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DOI: 10.3390/ijms23158628
Abstract: Muramyl dipeptide (N-acetylmuramyl-L-alanyl-D-isoglutamine, MDP) is the smallest peptidoglycan fragment able to trigger an immune response by activating the NOD2 receptor. Structural modification of MDP can lead to analogues with improved immunostimulating properties. The aim of… read more here.
Keywords: lipophilic triazole; evaluation mannosylated; immunological evaluation; synthesis immunological ... See more keywords