METHODS FOR THE SYNTHESIS OF INDOLE-3-CARBOXYLIC ACID ESTERS
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DOI: 10.1007/4728
Abstract: In this microreview, recent advances in the development of methods for indole cyclization, leading to indole-3-carboxylic acid derivatives, are highlighted. Selected works published since 2013 are covered. Authors: Valeriya A. Litvinova, Alexander S. Tikhomirov read more here.
Keywords: methods synthesis; indole carboxylic; acid esters; carboxylic acid ... See more keywords
Methods for the synthesis of indole-3-carboxylic acid esters (microreview)
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2370-3
Abstract: In this microreview, recent advances in the development of methods for indole cyclization, leading to indole-3-carboxylic acid derivatives, are highlighted. Selected works published since 2013 are covered. read more here.
Keywords: methods synthesis; indole carboxylic; acid esters; carboxylic acid ... See more keywords
Synthesis of indole-5,6- and carbazole-2,3-dicarboxylic acid functional derivatives
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DOI: 10.1007/s11172-017-1745-4
Abstract: Principal synthetic approaches to the synthesis of indole-5,6- and carbazole-2,3-dicarboxylic acid functional derivatives are considered. The first of them consists in the construction of the indole ring from simpler aromatic compounds containing carboxy groups, cyano… read more here.
Keywords: functional derivatives; dicarboxylic acid; carbazole dicarboxylic; indole carbazole ... See more keywords
Palladium-catalyzed synthesis of indole fused coumarins via cross-dehydrogenative coupling
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DOI: 10.1016/j.tetlet.2016.12.010
Abstract: Abstract The present method describes a palladium-catalyzed cross-dehydrogenative coupling reaction of coumarin and aniline for the synthesis of indole fused coumarin derivatives. The one-pot method is operationally simple and molecular oxygen is used as sole… read more here.
Keywords: cross dehydrogenative; indole fused; palladium catalyzed; dehydrogenative coupling ... See more keywords
Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions
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DOI: 10.1055/s-0037-1610223
Abstract: Isoquinolines activated with sulfamoyl chlorides were reacted with indoles in a 3-component reaction to generate a library of dihydroisoquinoline derivatives. Using a differential protecting group strategy, products could be further derivatised. Synthesis of isoquinoline starting… read more here.
Keywords: ureas via; sulfonyl ureas; dihydroisoquinoline; dihydroisoquinoline sulfonyl ... See more keywords
Facile, eco-friendly, one-pot protocol for the synthesis of indole-imidazole derivatives catalyzed by amino acids
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DOI: 10.1080/00397911.2017.1332766
Abstract: ABSTRACT An efficient, convenient green approach for the synthesis of indole-based 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles by multicomponent reaction of substituted 2-arylindole-3-carbaldehydes, benzil, substituted anilines, and ammonium acetate using catalytic amino acid (glycine) in ethanol is… read more here.
Keywords: facile eco; amino acids; eco friendly; friendly one ... See more keywords
β-cyclodextrin mediated synthesis of indole derivatives: reactions of isatins with 2-amino(or 2-thiole)anilines by supramolecular catalysis in water
Sign Up to like & getrecommendations! Published in 2018 at "Supramolecular Chemistry"
DOI: 10.1080/10610278.2018.1529315
Abstract: ABSTRACT An elegant, mild, and straightforward strategy for the synthesis of indole derivatives have been accomplished by the biomimetic catalysis for the first time in water under neutral conditions. This supramolecular catalyst oriented methodology provides… read more here.
Keywords: water; cyclodextrin; catalysis; indole derivatives ... See more keywords
Recent Developments on Synthesis of Indole Derivatives Through Green Approaches and Their Pharmaceutical Applications
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DOI: 10.2174/1385272824999201111203812
Abstract: Indole moiety is often found in different classes of pharmaceutically active molecules having various biological activities including anticancer, anti-viral, anti-psychotic, antihypertensive, anti-migraine, anti-arthritis and analgesic activities. Due to enormous applications of indole derivatives in pharmaceutical… read more here.
Keywords: methodology; chemistry; indole derivatives; green approaches ... See more keywords
Ruthenium-Catalyzed C–H Activations for the Synthesis of Indole Derivatives
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DOI: 10.3390/catal10111253
Abstract: The synthesis of substituted indoles has received great attention in the field of organic synthesis methodology. C–H activation makes it possible to obtain a variety of designed indole derivatives in mild conditions. Ruthenium catalyst, as… read more here.
Keywords: catalyzed activations; indole derivatives; activations synthesis; ruthenium catalyzed ... See more keywords
Chemoenzymatic Synthesis of Indole-Containing Acyloin Derivatives
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DOI: 10.3390/molecules28010354
Abstract: Indole-containing acyloins are either key intermediates of many antimicrobial/antiviral natural products or building blocks in the synthesis of biologically active molecules. As such, access to structurally diverse indole-containing acyloins has attracted considerable attention. In this… read more here.
Keywords: indole containing; chemoenzymatic synthesis; acyloin derivatives; synthesis indole ... See more keywords
Synthesis of the Indole-Based Inhibitors of Bacterial Cystathionine γ-Lyase NL1-NL3
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DOI: 10.3390/molecules28083568
Abstract: Bacterial cystathionine γ-lyase (bCSE) is the main producer of H2S in pathogenic bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, etc. The suppression of bCSE activity considerably enhances the sensitivity of bacteria to antibiotics. Convenient methods… read more here.
Keywords: bacterial cystathionine; synthesis indole; cystathionine lyase; indole based ... See more keywords