Synthesis and initial thermal behavior investigation of 2-alkenyl substituted pyrazine N-oxides
Sign Up to like & getrecommendations! Published in 2018 at "Catalysis Communications"
DOI: 10.1016/j.catcom.2018.07.017
Abstract: Abstract The systematic syntheses of 2-alkenylpyrazine N-oxides through palladium-catalyzed C-2 selective C H olefination reaction was disclosed. Various acrylate esters substituted pyrazine N-oxides were obtained in up to 93% yields. Thermogravimetric analysis indicated that the… read more here.
Keywords: substituted pyrazine; thermal behavior; initial thermal; pyrazine oxides ... See more keywords
A Mild Silica Gel Promoted Synthesis and Initial Functional Study of Tetrapyridyl Tetrahydropyrrolopyrrolones.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02095
Abstract: A one-pot strategy with yields up to 82% was reported to generate 2-(pyridin-2-yl)-2-(3,3a,6-tris(5-pyridin-2-yl)-5-oxohexahydropyrrolo[3,2-b] pyrrol-2(1H)-ylidene)acetonitrile 1a and its derivatives 1b-d. Silica gel promoted quantitative conversion from stable intermediate to 1a within 30 min at room temperature.… read more here.
Keywords: mild silica; initial functional; gel promoted; synthesis initial ... See more keywords
The Synthesis and Initial Evaluation of MerTK Targeted PET Agents
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051460
Abstract: MerTK (Mer tyrosine kinase), a receptor tyrosine kinase, is ectopically or aberrantly expressed in numerous human hematologic and solid malignancies. Although a variety of MerTK targeting therapies are being developed to enhance outcomes for patients… read more here.
Keywords: evaluation; mertk; initial evaluation; evaluation mertk ... See more keywords