Copper(I)-catalyzed synthesis of isoindolo[1,2-b]quinazoline derivatives via an α-arylation under Pd and ligand free conditions
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DOI: 10.1016/j.tetlet.2020.152508
Abstract: Abstract A tandem cyclization reaction of diethyl 2-(2-aminobenzamido)malonates and 2-bromobenzaldehydes was developed for the synthesis of isoindolo[1,2-b]quinazoline derivatives. The quinazoline was formed first catalyzed by CuI, followed by a noteworthy α-arylation reaction under Pd and… read more here.
Keywords: free conditions; ligand free; isoindolo quinazoline; quinazoline derivatives ... See more keywords