Decarbonylative Coupling of α-Keto Acids and Ynamides for Synthesis of β-Keto Imides.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b01302
Abstract: A novel decarbonylative coupling of α-keto acids and ynamides with extrusion of CO for synthesis of β-keto imides is reported. This process features mild reaction conditions, a broad substrate scope, and high efficiency. An isotope-labeling… read more here.
Keywords: decarbonylative coupling; acids ynamides; synthesis keto; keto ... See more keywords
Synthesis of β-keto sulfones via a multicomponent reaction through sulfonylation and decarboxylation
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DOI: 10.1039/c7qo00026j
Abstract: A copper(I)-catalyzed synthesis of β-keto sulfones through a multicomponent reaction of aryldiazonium tetrafluoroborates, 3-arylpropiolic acids, sulfur dioxide, and water was developed. This reaction proceeds through a tandem radical process, and the sulfonyl radical, generated from… read more here.
Keywords: multicomponent reaction; sulfonylation decarboxylation; synthesis keto; keto ... See more keywords
Facile Synthesis of β-Keto Sulfones Employing Fenton’s Reagent in DMSO
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DOI: 10.1055/s-0036-1589151
Abstract: A new facile method for the synthesis of β-keto sulfones employing xanthates, DMSO, and Fenton’s reagent is described. The reaction proceeds under very mild conditions providing a cost-effective straightforward approach to various β-keto sulfones in… read more here.
Keywords: fenton reagent; synthesis keto; keto; keto sulfones ... See more keywords
Corrigendum: Enzymatic Synthesis of 2-Keto-3-Deoxy-6-Phosphogluconate by the 6-Phosphogluconate-Dehydratase From Caulobacter crescentus
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00761
Abstract: [This corrects the article DOI: 10.3389/fbioe.2020.00185.]. read more here.
Keywords: phosphogluconate; corrigendum enzymatic; enzymatic synthesis; keto deoxy ... See more keywords
Chemoenzymatic Total Synthesis of (+)-10-Keto-Oxycodone from Phenethyl Acetate †
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DOI: 10.3390/molecules24193477
Abstract: The total synthesis of (+)-10-keto-oxycodone was attained from phenethyl acetate in a stereoselective manner. Absolute stereochemistry was established via enzymatic dihydroxylation of phenethyl acetate with the recombinant strain JM109 (pDTG601A) that furnished the corresponding cis-cyclohexadienediol… read more here.
Keywords: total synthesis; phenethyl acetate; synthesis keto; keto ... See more keywords