Articles with "synthesis lactams" as a keyword



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Diastereoselective Synthesis of γ-Lactams and δ-Lactams via a Conjugate Addition-Initiated Tandem Reaction

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Published in 2019 at "Synlett"

DOI: 10.1055/s-0037-1611552

Abstract: β-Alkoxycarbonyl-γ-lactams and γ-alkoxycarbonyl-δ-lactams were synthesized via a conjugate alkylation/Mannich reaction/lactamization tandem reaction of unsaturated dicarboxylates with diethyl zinc and aldimines. The high yield, the ready availability of the reagents, and especially the high diastereoselectivity are… read more here.

Keywords: tandem reaction; diastereoselective synthesis; synthesis lactams; via conjugate ... See more keywords
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Stereocontrol in the Synthesis of β-Lactams Arising from the Interlocked Structure of Benzylfumaramide-Based Hydrogen-Bonded [2]Rotaxanes

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Published in 2019 at "Synlett"

DOI: 10.1055/s-0037-1611705

Abstract: β-Lactams are highly valuable compounds due to their antibiotic activity. Among the number of well-established methodologies for building this privileged scaffold, our research group has settled on a novel synthetic approach for their preparation. This… read more here.

Keywords: benzylfumaramide based; synthesis; synthesis lactams; cyclization ... See more keywords
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Synthesis of Lactams via Isocyanide-Based Multicomponent Reactions

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Published in 2020 at "Synthesis"

DOI: 10.1055/s-0040-1706297

Abstract: Lactams are very important heterocycles as a result of their presence in a wide range of bioactive molecules, natural products and drugs, and also due their utility as versatile synthetic intermediates. Due to these reasons,… read more here.

Keywords: multicomponent reactions; lactams lactams; isocyanide based; based multicomponent ... See more keywords