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Published in 2019 at "Synlett"
DOI: 10.1055/s-0037-1611552
Abstract: β-Alkoxycarbonyl-γ-lactams and γ-alkoxycarbonyl-δ-lactams were synthesized via a conjugate alkylation/Mannich reaction/lactamization tandem reaction of unsaturated dicarboxylates with diethyl zinc and aldimines. The high yield, the ready availability of the reagents, and especially the high diastereoselectivity are…
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Keywords:
tandem reaction;
diastereoselective synthesis;
synthesis lactams;
via conjugate ... See more keywords
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Published in 2019 at "Synlett"
DOI: 10.1055/s-0037-1611705
Abstract: β-Lactams are highly valuable compounds due to their antibiotic activity. Among the number of well-established methodologies for building this privileged scaffold, our research group has settled on a novel synthetic approach for their preparation. This…
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Keywords:
benzylfumaramide based;
synthesis;
synthesis lactams;
cyclization ... See more keywords
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Published in 2020 at "Synthesis"
DOI: 10.1055/s-0040-1706297
Abstract: Lactams are very important heterocycles as a result of their presence in a wide range of bioactive molecules, natural products and drugs, and also due their utility as versatile synthetic intermediates. Due to these reasons,…
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Keywords:
multicomponent reactions;
lactams lactams;
isocyanide based;
based multicomponent ... See more keywords