Synthesis of Leu-Enkephalin Peptidomimetics Containing Trifluoromethylalkenes as Amide Isopolar Mimics.
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DOI: 10.1016/j.jfluchem.2018.12.005
Abstract: Fluorinated peptidomimetics are valuable substrates for exploring peptide backbone conformations and for perturbing physicochemical properties of probe compounds. However, in some cases synthetic limitations restrict installation of the fluorinated peptidomimetics into the desired probe compounds.… read more here.
Keywords: synthesis leu; isopolar mimics; leu enkephalin; amide isopolar ... See more keywords