Catalytic, Asymmetric Total Synthesis of (+)-α-, (+)-β-, (+)-γ-, and (-)-δ-Lycorane.
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DOI: 10.1021/acs.orglett.2c00905
Abstract: The first collectively asymmetric total synthesis of all members of lycorane, including (+)-α, (+)-β, (+)-γ, and (-)-δ, in a catalytic manner has been achieved. The cornerstone of this synthesis features an asymmetric, stereodivergent Ir/amine dual… read more here.
Keywords: synthesis lycorane; synthesis; asymmetric total; total synthesis ... See more keywords
A Four-Step Synthesis of (±)-γ-Lycorane via Pd0-Catalyzed Double C(sp2)-H/C(sp3)-H Arylation.
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DOI: 10.1021/acs.orglett.7b03909
Abstract: An expedient synthesis of lycorine alkaloids is reported using a palladium(0)-catalyzed double C-X/C-H arylation as the key step. The selectivity of this reaction was controlled through the judicious choice of the two halogen atoms, and… read more here.
Keywords: catalyzed double; step; arylation; synthesis lycorane ... See more keywords