Sign Up to like & get
recommendations!
1
Published in 2022 at "Bioorganic chemistry"
DOI: 10.2139/ssrn.4063470
Abstract: Herein, the design, synthesis and mechanistic study of five series of imidazo[1,2-a]pyridines 8a-d, 9a-f, 11a-c, 12a-d and 14a-d as anticancer agents were discussed. The cytotoxicity of imidazo[1,2-a]pyridine derivatives was screened against NCI 60 cancer cell…
read more here.
Keywords:
design synthesis;
cell;
imidazo pyridines;
leukemia 562 ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11081126
Abstract: Methionine aminopeptidases (MetAPs) are attractive drug targets due to their essential role in eukaryotes as well as prokaryotic cells. In this study, biochemical assays were performed on newly synthesized Isatin-pyrazole hydrazones (PS1–14) to identify potent…
read more here.
Keywords:
design synthesis;
ps9 inhibited;
selective bacterial;
bacterial strains ... See more keywords