Transition metal catalyzed C-H activation for the synthesis of medicinally relevant molecules: A Review
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DOI: 10.1007/s12039-018-1468-6
Abstract: C-H activation in the synthesis of medicinally relevant molecules is reviewed. C-H activation is one of the most powerful components in the C-C or C-heteroatom bond formation tool box. This represents such an alternative which… read more here.
Keywords: relevant molecules; chemistry; medicinally relevant; synthesis medicinally ... See more keywords
A happy medium: the synthesis of medicinally important medium-sized rings via ring expansion
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DOI: 10.1039/d0sc00568a
Abstract: Medium-sized rings have much promise in medicinal chemistry, but are difficult to make using direct cyclisation methods. In this minireview, we highlight the value of ring expansion strategies to address this long-standing synthetic challenge. We… read more here.
Keywords: ring expansion; medium; medium sized; synthesis medicinally ... See more keywords
An efficient synthesis of medicinally important indole based triarylmethanes by using propylphosphonic anhydride (T3P®)
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DOI: 10.1080/00397911.2020.1743319
Abstract: Abstract We have developed an economical and efficient method for the synthesis of medicinally and synthetically important indole-based triarylmethanes by using indoles and benzhydrols in the presence of propylphosphonic anhydride (T3P®). This methodology is an… read more here.
Keywords: based triarylmethanes; propylphosphonic anhydride; synthesis medicinally; important indole ... See more keywords
Synthesis of Medicinally Relevant Scaffolds-Triazoles and Pyrazoles in Green Solvent Ionic Liquids
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DOI: 10.2174/1385272825666210412160142
Abstract: The use of natural and environment friendly energy sources for betterment of the living society has become an active concern in both government and public sector. Due to this, responsible use of global resources has… read more here.
Keywords: medicinally relevant; relevant scaffolds; synthesis medicinally; scaffolds triazoles ... See more keywords
Heterogeneous Metal Catalysis for the Environmentally Benign Synthesis of Medicinally Important Scaffolds, Intermediates, and Building Blocks
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DOI: 10.2174/1385272825666210519095808
Abstract: This account provides a broad overview of the application of solid metal catalysts in synthetic chemistry with a focus on the synthesis of medicinally important scaffolds or building blocks. Heterogeneous catalysis is a fundamental contributor… read more here.
Keywords: building blocks; important scaffolds; chemistry; synthesis medicinally ... See more keywords