Asymmetric Synthesis of 3-Methyleneindolines via Rhodium(I)-Catalyzed Alkynylative Cyclization of N-(o-Alkynylaryl)imines.
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DOI: 10.1021/acs.orglett.1c01518
Abstract: The first asymmetric synthesis of 3-methyleneindolines from alkynyl imines has been developed via a rhodium-catalyzed tandem process: regioselective alkynylation of the internal alkynes and subsequent intramolecular addition to the imines. The reaction proceeded with unconventional… read more here.
Keywords: via rhodium; rhodium catalyzed; synthesis methyleneindolines; asymmetric synthesis ... See more keywords