Articles with "synthesis methylidenepyrrol" as a keyword



Selective Synthesis of 2-Methylidenepyrrol-3-Ones from Diynones and Amines

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Published in 2019 at "Chemistry of Heterocyclic Compounds"

DOI: 10.1007/s10593-019-02515-4

Abstract: Addition of primary amines to 1-phenyl-5-trimethylsilylpenta-1,4-diyn-3-one with subsequent cyclization affords 5-phenyl-2-(trimethylsilylmethylidene)-1,2-dihydro-3H-pyrrol-3-ones. Both electron-rich and electron-deficient anilines and alkyl amines provide regio- and stereoselective formation of single product in high yields. The two-step transformation benefits from… read more here.

Keywords: ones diynones; selective synthesis; diynones amines; methylidenepyrrol ones ... See more keywords