Total synthesis of (+)-methynolide using a Ti-mediated aldol reaction of a lactyl-bearing oxazolidin-2-one, and a vinylogous Mukaiyama aldol reaction
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DOI: 10.1016/j.tet.2017.03.093
Abstract: A bstract A highly convergent total synthesis of (+)-methynolide, based on two types of stereoselective aldol reaction, was achieved. The C1-C8 and C9-C11 fragments of (+)-methynolide were prepared by a vinylogous Mukaiyama aldol reaction using… read more here.
Keywords: aldol reaction; synthesis methynolide; total synthesis; reaction ... See more keywords