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1
Published in 2022 at "ChemCatChem"
DOI: 10.1002/cctc.202200140
Abstract: Molnupiravir (Lagevrio®) is an orally‐administered anti‐COVID‐19 agent. Due to the urgency to meet the worldwide demand and the growing environmental concern, there is a need for speed in the industrial implementation of novel and efficient…
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Keywords:
molnupiravir paving;
mediated synthesis;
synthesis;
enzyme mediated ... See more keywords
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2
Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.1c00772
Abstract: Molnupiravir (MK-4482, EIDD-2801) is a promising orally bioavailable drug candidate for the treatment of COVID-19. Herein, we describe a supply-centered and chromatography-free synthesis of molnupiravir from cytidine, consisting of two steps: a selective enzymatic acylation…
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Keywords:
molnupiravir 4482;
molnupiravir;
synthesis molnupiravir;
4482 eidd ... See more keywords
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1
Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra05064a
Abstract: A concise synthesis of molnupiravir in a one-pot two-step approach starting from uridine is described. Formally, herein, two sets of one-pot two-reaction steps introducing simplicity for purifications and using chemically available reagents are presented. In…
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Keywords:
two step;
concise two;
synthesis molnupiravir;