Silica gel-promoted synthesis of multisubstituted spiroindolenines from tryptamines and γ-chloro-α,β-unsaturated ketones
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron"
DOI: 10.1016/j.tet.2020.131765
Abstract: ABSTRACT Here we report a one-pot synthesis of multisubstituted spiroindolenines from a series of tryptamine derivatives with γ-chloro-α,β-unsaturated ketones. The reaction sequence consists of base-induced condensation and silica gel-promoted intramolecular Michael addition. The target molecules… read more here.
Keywords: unsaturated ketones; synthesis multisubstituted; multisubstituted spiroindolenines; chloro unsaturated ... See more keywords
Synthesis of Multisubstituted Allenes via Palladium-Catalyzed Cross-Coupling Reaction of Propargyl Acetates with an Organoaluminum Reagent
Sign Up to like & getrecommendations! Published in 2017 at "Synlett"
DOI: 10.1055/s-0036-1588389
Abstract: We describe a convenient method for the synthesis of multisubstituted allenes from cross-coupling of propargyl acetates with organoaluminum reagent: The reaction of propargyl acetates with 1.2 equivalents of organoaluminum reagent mediated by Pd(PPh 3 ) 2… read more here.
Keywords: organoaluminum reagent; multisubstituted allenes; synthesis multisubstituted; propargyl acetates ... See more keywords
Synthesis of Multisubstituted Guanidines through Palladium-Catalyzed Insertion of Isonitriles
Sign Up to like & getrecommendations! Published in 2018 at "Synlett"
DOI: 10.1055/s-0037-1610981
Abstract: A new method for the synthesis of multisubstituted guanidines through tandem intermolecular insertion of isonitriles with unactivated amides has been developed. In this study, isonitriles could be used not only as reaction materials but also… read more here.
Keywords: synthesis multisubstituted; multisubstituted guanidines; insertion isonitriles; palladium catalyzed ... See more keywords