Computational study of Simultaneous synthesis of optically active (RS)-1,2,4-butanetriol trinitrate (BTTN)
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DOI: 10.1007/s00894-017-3414-9
Abstract: AbstractIn respective water or ethanol polarizable continuum cavity environments, simultaneous aldol condensation was performed using density functional theory (DFT) computational method to model the synthesis of optically active (RS)-1,2,4-butanetriol trinitrate (BTTN). The results of reaction… read more here.
Keywords: optically active; synthesis optically; active butanetriol; butanetriol trinitrate ... See more keywords
Synthesis of Optically Active Macrolides From L-Menthone Derivatives and Hydrazides of Adipic and 2,6-Pyridinedicarboxylic Acids
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DOI: 10.1007/s10600-018-2387-y
Abstract: Efficient syntheses of two potentially useful optically active macroheterocycles with esters and dihydrazides of 2,6-pyridinedicarboxylic and adipic acids starting from available natural L-menthol and passing through intermediate 8-hydroxy-2,6R-dimethyloctan-3-one were developed. The key steps were [2… read more here.
Keywords: optically active; synthesis optically; macrolides menthone; active macrolides ... See more keywords
Synthesis of optically active 2,7-disubstituted naphthalene derivatives and evaluation of their enantioselective recognition ability
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DOI: 10.1007/s11172-020-2910-8
Abstract: The palladium-catalyzed amination was used to synthesize 2,7-diamino derivatives of naphthalene containing two chiral substituents and fluorophore groups (dansyl, 7-methoxycoumarin, 6,7-dimethoxycoumarin, 6-aminoquinoline). The synthesized compounds were studied by UV absorption and fluorescence spectroscopy in the… read more here.
Keywords: optically active; synthesis optically; naphthalene derivatives; recognition ... See more keywords
Preparation of 2,3-trans-substituted piperidines from optically active β-amino-α-methylene esters: Synthesis of optically active (2S,3R)-(−)-epi-CP-99,994
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DOI: 10.1016/j.tet.2017.06.054
Abstract: Abstract Chiral 2,3- trans -substituted piperidines were readily prepared in three steps from β-amino-α-methylene esters, which were prepared by the Michael/Mannich domino reaction of chiral sulfinimines. Hydrogenation of the N -tosyl-2-aryl-1,2,5,6-tetrahydropyridine intermediates took place smoothly… read more here.
Keywords: optically active; synthesis optically; trans substituted; methylene esters ... See more keywords
Synthesis of Optically Active syn- and anti-Chlorohydrins through a Bienzymatic Reductive Cascade
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DOI: 10.1021/acs.orglett.2c02592
Abstract: A bienzymatic cascade has been designed and optimized to obtain enantiopure chlorohydrins starting from the corresponding 1-aryl-2-chlorobut-2-en-1-ones. For the synthesis of these α-chloroenones, a two-step sequence was developed consisting of the allylation of the corresponding… read more here.
Keywords: cascade; active syn; optically active; anti chlorohydrins ... See more keywords
Synthesis of Optically Active Organofluorides by Ring Opening of Oxazolidinone-Fused Aziridines.
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DOI: 10.1021/acs.orglett.2c04042
Abstract: A general method for synthesizing optically active, primary, secondary, and tertiary organofluorides was developed. This chiral pool synthesis utilized the skeleton of arabinose to generate diastereomerically pure 2-oxazolidinone-fused aziridines, which underwent ring opening with a… read more here.
Keywords: fused aziridines; oxazolidinone fused; optically active; ring opening ... See more keywords
Stereoselective Chemoenzymatic Synthesis of Optically Active Aryl-Substituted Oxygen-Containing Heterocycles
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DOI: 10.3390/catal7020037
Abstract: A two-step stereoselective chemoenzymatic synthesis of optically active α-aryl-substituted oxygen heterocycles was developed, exploiting a whole-cell mediated asymmetric reduction of α-, β-, and γ-chloroalkyl arylketones followed by a stereospecific cyclization of the corresponding chlorohydrins into… read more here.
Keywords: optically active; oxygen; synthesis optically; aryl substituted ... See more keywords
Synthesis of Optically and Redox Active Polyenaminones from Diamines and α,α’-Bis[(dimethylamino)methylidene]cyclohexanediones
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DOI: 10.3390/polym14194120
Abstract: New oligo- and polyenaminones with Mw ~ 7–50 KDa were prepared in high yields by transaminative amino-enaminone polymerization of regioisomeric bis[(dimethylamino)methylidene]cyclohexanediones with alkylene and phenylenediamines. The polymers obtained are practically insoluble in aqueous and organic… read more here.
Keywords: synthesis optically; bis dimethylamino; methylidene cyclohexanediones; dimethylamino methylidene ... See more keywords