A de novo Synthesis of Oxindoles from Cyclohexanone-Derived γ-Keto-ester Acceptors Using a Desaturative Amination–Cyclization Approach
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DOI: 10.1055/a-1538-8429
Abstract: Here we report a desaturative approach for oxindole synthesis. This method uses simple γ-ester-containing cyclohexanones and primary amine building blocks as coupling partners. A dual photoredox–cobalt manifold is used to generate a secondary aniline that,… read more here.
Keywords: synthesis oxindoles; novo synthesis; ester; approach ... See more keywords