Articles with "synthesis point" as a keyword



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Synthesis of point-modified mRNA

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Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac719

Abstract: Abstract Synthetic mRNA has recently moved into the focus of therapeutic and vaccination efforts. Incorporation of modified nucleotides during in vitro transcription can improve translation and attenuate immunogenicity, but is limited to triphosphate nucleotides which… read more here.

Keywords: point modified; incorporation; modified mrna; synthesis point ... See more keywords