Synthesis of β-Polychlorinated Alkynes Enabled by Copper-Catalyzed Multicomponent Reaction.
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DOI: 10.1021/acs.orglett.2c01755
Abstract: Functional molecules bearing polychlorinated moieties usually play versatile roles in organic synthesis and biochemistry. A copper-catalyzed multicomponent polychloro-carboalkynylation of alkenes presents an efficient and operationally simple approach for the synthesis of β-polychlorinated alkynes. Mechanistic experiments… read more here.
Keywords: synthesis polychlorinated; copper; polychlorinated alkynes; catalyzed multicomponent ... See more keywords