Diastereoselective synthesis of polyfluoroalkylated α-aminophosphonic acid derivatives
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DOI: 10.1016/j.jfluchem.2018.10.001
Abstract: Abstract The asymmetric synthesis of biorelevant aminophosphonates and aminophosphonic acids bearing trifluoromethyl, tetrafluoroethyl, perfluoropropyl or chlorodifluoromethyl group in the α-position to phosphonyl group is developed. Diastereoselective reduction of α-(poly)fluoroalkylated iminophosphonates, bearing stereodirecting α-phenylethyl group at… read more here.
Keywords: aminophosphonic acid; diastereoselective synthesis; group; synthesis polyfluoroalkylated ... See more keywords