One‐Pot Synthesis of Polysubstituted Indoles via the Indium‐Promoted Regioselective Hydrohydrazination of Terminal Alkynes
Sign Up to like & getrecommendations! Published in 2025 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.202400682
Abstract: We demonstrated that indium bromide, a trivalent indium compound with strong tolerance toward various coordination functional groups, can be used as a sole promotor to effectively promote the hydrohydrazination of a variety of N‐phenylhydrazines with… read more here.
Keywords: one pot; indium; hydrohydrazination; synthesis polysubstituted ... See more keywords
One‐pot synthesis of polysubstituted pyrrolidinones using novel magnetic nanoparticles as an efficient and reusable catalyst
Sign Up to like & getrecommendations! Published in 2017 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.3681
Abstract: 7-Aminonaphthalene-1,3-disulfonic acid-functionalized magnetic Fe3O4 nanoparticles efficiently catalyse the one-pot multi-component synthesis of substituted 3-pyrrolin-2-ones without using any other harmful organic reagents. High catalytic activity, ease of recovery, use of an external magnetic field and capability… read more here.
Keywords: synthesis polysubstituted; catalyst; pot synthesis; one pot ... See more keywords
Synthesis of Polysubstituted Bicyclo[3.1.0]Hexanes via Boronyl Radical Catalyzed [3 + 2] Cycloaddition of Cyclopropanes with Cyclopropenes
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DOI: 10.1002/cctc.202401909
Abstract: Bicyclo[3.1.0]hexane is a key structural unit in numerous natural products and small molecule drugs. The efficient and sustainable construction of this skeleton is of particular importance. Herein, we report a boronyl radical‐catalyzed [3 + 2]… read more here.
Keywords: cyclopropanes cyclopropenes; catalyzed cycloaddition; synthesis polysubstituted; polysubstituted bicyclo ... See more keywords
Synthesis of Polysubstituted 3‐Methylisoquinolines through the 6π‐Electron Cyclization/Elimination of 1‐Azatrienes derived from 1,1‐Dimethylhydrazine
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201801076
Abstract: Fil: Vargas Vargas, Didier Farley. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Rosario. Instituto de Quimica Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Bioquimicas y Farmaceuticas. Instituto de Quimica… read more here.
Keywords: synthesis polysubstituted; methylisoquinolines electron; rosario; cyclization elimination ... See more keywords
Organocatalytic Cascade Knoevenagel–Michael Addition Reactions: Direct Synthesis of Polysubstituted 2-Amino-4H-Chromene Derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Catalysis Letters"
DOI: 10.1007/s10562-019-03089-8
Abstract: In this report, we documented novel strategy for the synthesis of bioactive polysubstituted 2-amino-4H-chromine derivatives under a heterogeneous Al-MCM-41-LDH@APTES (ALAM) catalysis. A synthetic procedure is developed to prepare Al-MCM-41-LDH@APTES (ALAM) heterogeneous basic catalysts. Mesoporous Al-MCM-41… read more here.
Keywords: synthesis polysubstituted; michael addition; polysubstituted amino; addition reactions ... See more keywords
Synthesis of di- and trihydroxy proline derivatives from D-glycals: Application in the synthesis of polysubstituted pyrrolizidines and bioactive 1C-aryl/alkyl pyrrolidines.
Sign Up to like & getrecommendations! Published in 2019 at "Carbohydrate research"
DOI: 10.1016/j.carres.2019.02.004
Abstract: Six different types of O-benzyl protected proline derivatives have been synthesized from D-glycals and 2C-formyl-glycals. One of the di-O-benzyl protected proline derivatives has been utilized for the synthesis of polysubstituted pyrrolizidines via [3 + 2] cycloaddition in… read more here.
Keywords: synthesis polysubstituted; synthesis; proline derivatives; aryl alkyl ... See more keywords
DBU-promoted tandem Michael-addition/cyclization for the synthesis of polysubstituted pyrroles
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron"
DOI: 10.1016/j.tet.2019.02.057
Abstract: Abstract An efficient and transition-metal-free method for the synthesis of the structurally diversified pyrroles is described. Various α,β-unsaturated ynones reacted with N-substituted ethyl glycine ethyl ester hydrochlorides in the presence of DBU to form the… read more here.
Keywords: synthesis; promoted tandem; polysubstituted pyrroles; synthesis polysubstituted ... See more keywords
Synthesis of Polysubstituted Germoles and Benzogermoles Using a Substoichiometric Amount of Diisobutylaluminum Hydride.
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DOI: 10.1021/acs.orglett.1c01314
Abstract: We developed a synthetic route to unsymmetrically polysubstituted germoles bearing different substituents from 1-hydrogermyl-4-silyl-1,3-enynes. The reaction proceeded with 0.5 equiv of diisobutylaluminum hydride. Various 2-silylgermoles including benzogermoles were obtained in good to excellent yields. 2-Germylbenzogermoles… read more here.
Keywords: diisobutylaluminum hydride; synthesis polysubstituted; benzogermoles using; polysubstituted germoles ... See more keywords
Phenanthrenequinone-Sensitized Photocatalytic Synthesis of Polysubstituted Quinolines from 2-Vinylarylimines.
Sign Up to like & getrecommendations! Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c03934
Abstract: Visible-light-excited 9,10-phenanthrenequinone (PQ*) was used as a photocatalyst for the synthesis of polysubstituted quinolines via the electrocyclization of 2-vinylarylimines. Up to quantitative yields of 2,4-disubstituted quinolines were received after 1 h of excitation with blue… read more here.
Keywords: polysubstituted quinolines; synthesis polysubstituted; photocatalytic synthesis; sensitized photocatalytic ... See more keywords
Modular Synthesis of Polysubstituted α-Phosphorylated Arenes via the Catellani Strategy.
Sign Up to like & getrecommendations! Published in 2024 at "Organic letters"
DOI: 10.1021/acs.orglett.4c01944
Abstract: In this paper, we described a palladium/norbornene-catalyzed ortho-C-H phosphormethylation of aryl iodides using XCH2P(O)RR', offering a reliable method for the modular synthesis of polysubstituted α-phosphorylated arenes. Alkenylation, hydrogenation, cyanation, methylation, and arylation were all viable… read more here.
Keywords: arenes via; synthesis polysubstituted; polysubstituted phosphorylated; modular synthesis ... See more keywords
A multicomponent two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-ones using a solid acid as a recyclable catalyst
Sign Up to like & getrecommendations! Published in 2019 at "Green Chemistry"
DOI: 10.1039/c9gc01120j
Abstract: A two-step strategy for the synthesis of polysubstituted pyrrolo[3,2-c]pyridin-4-ones using a solid acid as a recyclable catalyst. read more here.
Keywords: two step; strategy synthesis; polysubstituted pyrrolo; pyrrolo pyridin ... See more keywords