Synthesis of ponatinib analogues as novel inhibitors of leukemia stem cells.
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DOI: 10.4155/fmc-2022-0038
Abstract: Aim: To synthesize new analogues of ponatinib and evaluate anti-leukemia cells and cytotoxicity. Methodology & results: The inhibitory activity of compounds 13a and 13c against K562 and HL60 cells was comparable to that of ponatinib… read more here.
Keywords: novel inhibitors; analogues novel; ponatinib analogues; synthesis ponatinib ... See more keywords