Indium-Catalyzed Intramolecular Hydroamidation of Alkynes: An Exo-Dig Cyclization for the Synthesis of Pyranoquinolines through Post-Transformational Reaction.
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DOI: 10.1021/acs.orglett.7b02603
Abstract: An efficient approach for the synthesis of pyranoquinolines through the indium-catalyzed activation of alkynes is reported. Intramolecular hydroamidation of alkynes can proceed through alkyne activation by indium(III) and then 6-exo-dig cyclization, leading to a fused… read more here.
Keywords: intramolecular hydroamidation; hydroamidation alkynes; synthesis pyranoquinolines; cyclization ... See more keywords