CURRENT APPROACHES TO THE SYNTHESIS OF PYRROLO[2,1- a ]ISOQUINOLINES
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DOI: 10.1007/4989
Abstract: This microreview considers methods for the synthesis of pyrrolo[2,1-a]isoquinolines, published from year 2014 until 2018. read more here.
Keywords: approaches synthesis; synthesis pyrrolo; chemistry; pyrrolo isoquinolines ... See more keywords
Synthesis of pyrrolo[2,3-d]pyrimidines (microreview)
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DOI: 10.1007/s10593-019-02595-2
Abstract: Microreview summarizes recent methods for the synthesis of pyrrolo[2,3-d]pyrimidines, published since 2015. The methods are classified as Cu-catalyzed reactions, microwave-assisted reactions, pyrrole-based reactions, Fischer indole-type synthesis, and aldehyde-based reactions. read more here.
Keywords: pyrrolo pyrimidines; pyrimidines microreview; synthesis; synthesis pyrrolo ... See more keywords
Synthesis of pyrrolo[3,4-c]pyridine-1,3-diones (5-azaphthalimides) (microreview)
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DOI: 10.1007/s10593-020-02693-6
Abstract: The review summarizes the work devoted to the preparation of pyrrolo[3,4-c]pyridine-1,3-dione (5-azaphthalimide) derivatives over the last 10 years. Methods for the synthesis of pyrrolo[3,4-c]pyridine-1,3-dione derivatives are divided into three groups: annulation of the pyrrole moiety,… read more here.
Keywords: pyridine diones; pyrrolo pyridine; pyridine; synthesis pyrrolo ... See more keywords
N-Heterocyclic Carbene-Catalyzed Atroposelective Synthesis of Pyrrolo[3,4-b]pyridines with Configurationally Stable C-N Axial Chirality.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c01519
Abstract: The first atroposelective synthesis of pyrrolo[3,4-b]pyridines catalyzed by N-heterocyclic carbene has been achieved. A wide range of chiral atropisomers of pyrrolo[3,4-b]pyridines were obtained in high yields with excellent enantioselectivities (96-99% enantiomeric excess). The experimental results… read more here.
Keywords: pyrrolo pyridines; axial chirality; synthesis pyrrolo; atroposelective synthesis ... See more keywords
Rhodium(III)-Catalyzed Intramolecular Annulation and Aromatization for the Synthesis of Pyrrolo[1,2-a]quinolines.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c00321
Abstract: A rhodium(III)-catalyzed protocol for the synthesis of pyrrolo[1,2-a]quinolines through intramolecular annulation of o-alkynyl amino aromatic ketones and subsequent aromatization is reported. This transformation builds the pyrrole and quinoline moieties of the pyrrolo[1,2-a]quinoline in one pot… read more here.
Keywords: intramolecular annulation; pyrrolo quinolines; rhodium iii; synthesis pyrrolo ... See more keywords
Synthesis of Pyrrolo[2,3-c]isoquinolines via the Cycloaddition of Benzyne with Arylideneaminopyrroles: Photophysical and Crystallographic Study
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DOI: 10.1021/acsomega.9b02043
Abstract: An efficient and quick access toward a series of (E)-2-arylideneaminopyrroles 6 and to their benzyne-promoted aza-Diels–Alder cycloaddition products is provided. These products are three pyrrolo[2,3-c]isoquinolines 8a–c substituted in position 5 with different electron-acceptor (A) or… read more here.
Keywords: cycloaddition; synthesis pyrrolo; study; isoquinolines via ... See more keywords
FeCl3-Catalyzed synthesis of pyrrolo[1,2-a]quinoxaline derivatives from 1-(2-aminophenyl)pyrroles through annulation and cleavage of cyclic ethers.
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DOI: 10.1039/c7cc07089f
Abstract: A straightforward Fe-catalyzed method for the synthesis of pyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and cyclic ethers, which includes functionalization of C(sp3)-H bonds and the construction of C-C and C-N bonds, has been developed. The features of this… read more here.
Keywords: aminophenyl pyrroles; synthesis pyrrolo; pyrrolo; cyclic ethers ... See more keywords
Synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones via addition/cyclization reactions between 3-chloro-4-indolylmaleimides and alkynes
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DOI: 10.1177/1747519820909456
Abstract: 3-Chloro-4-indolylmaleimides and two different alkynes are used as the starting materials in a novel and highly effective Pd-catalyzed addition/C–H activation/cyclization sequence for the synthesis of pyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones. The desired products are obtained in moderate to excellent… read more here.
Keywords: addition; synthesis pyrrolo; cyclization; carbazole diones ... See more keywords
Total synthesis of pyrrolo[2,3-c]quinoline alkaloid: trigonoine B
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DOI: 10.3762/bjoc.17.62
Abstract: The first total synthesis of the pyrrolo[2,3-c]quinoline alkaloid trigonoine B (1) was accomplished via a six-step sequence involving the construction of an N-substituted 4-aminopyrrolo[2,3-c]quinoline framework via electrocyclization of 2-(pyrrol-3-yl)benzene containing a carbodiimide moiety as a… read more here.
Keywords: synthesis pyrrolo; pyrrolo quinoline; quinoline alkaloid; total synthesis ... See more keywords