Design, Synthesis and X-ray Structural Studies of Potent HIV-1 Protease Inhibitors Containing C-4 Substituted Tricyclic Hexahydro-furofuran derivatives as P2 ligands.
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200058
Abstract: The design, synthesis, X-ray structural, and biological evaluation of a series of highly potent HIV-1 protease inhibitors are reported herein. These inhibitors incorporated novel cyclohexane-fused tricyclic bis -tetrahydrofuran as P2 ligands in combination with a… read more here.
Keywords: synthesis ray; protease; potent hiv; hiv protease ... See more keywords
Synthesis, X-ray structure and theoretical investigation of 2-(2’-quinolyl)benzimidazole metal complexes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Chemical Sciences"
DOI: 10.1007/s12039-016-1210-1
Abstract: AbstractSynthesis, characterization and DFT analysis of 2-(1H-benzo[d]imidazol-2-yl)quinoline (BQ) and its cobalt and manganese coordination compounds {Co(DMF)(BQ) Cl 2} and {Mn(DMF)(BQ) Cl 2} have been described. The ligand, 2-(1H-benzo[d]imidazol-2-yl)quinoline (BQ) crystallizes in non-centrosymmetric monoclinic crystal system… read more here.
Keywords: benzo imidazol; metal; imidazol quinoline; synthesis ray ... See more keywords
Synthesis and X-ray crystal structures of three new nickel(II) complexes of benzoylhydrazones: Catalytic applications in the synthesis of 2-arylbenzoxazoles
Sign Up to like & getrecommendations! Published in 2020 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2019.119222
Abstract: Abstract Three new complexes of nickel(II), having general formula [Ni(L1)(PPh3)] (1), [Ni(L1)(4-picoline)] (2), and [Ni(L2)(4-picoline)] (3) were synthesized by the reaction of Ni(OAc)2·4H2O with corresponding benzolyhydrazine-derived Schiff base ligands i.e. [4-(diethylamino)-2-hydroxybenzylidene]-benzohydrazonic acid (H2L1) or [2-(hydroxynaphthalen-1-yl)methylene]-benzohydrazonic… read more here.
Keywords: three new; synthesis ray; three complexes; structures three ... See more keywords
Synthesis and X-Ray crystallography of a substituted trityl fluoride: Ordering power of a C-F bond
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2019.109377
Abstract: Abstract Herein we report the synthesis and X-ray crystallographic study of a per(meta-t-butyl) substituted trityl fluoride in order to explore possible intermolecular F F interactions, as inspired by the recent work of Schreiner et al.… read more here.
Keywords: synthesis ray; substituted trityl; trityl fluoride; ray crystallography ... See more keywords
Synthesis, X-ray structural determination and biological evaluation of novel ferrocene grafted spiroquinoxalinopyrrolidine
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DOI: 10.1016/j.molstruc.2020.129348
Abstract: Abstract Synthesis of a hybrid heterocycle comprising ferrocene, spiropyrrolidine and quinoxaline structural moieties have been achieved in good yield via ionic liquid expedited multicomponent 1,3-dipolar cycloaddition reaction. Structural properties of the synthesized compound were exploited… read more here.
Keywords: ray structural; biological evaluation; determination biological; synthesis ray ... See more keywords
{Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c6dt04295c
Abstract: The reaction of [Ru(CO)6Cl2], 1, with N[combining low line]3-methylbenzimidazole (MBI) and 5,6-dimethylbenzimidazole (DMBI) afforded two new complexes with the general formula fac-[RuII(CO)3Cl2L], L = MBI (2) or DMBI (4). Crystals of cis,trans-[RuII(CO)2Cl2(N[combining low line]3-MBI)2], 3,… read more here.
Keywords: ligands synthesis; complexes benzimidazole; core complexes; synthesis ray ... See more keywords
N-(2,3,5,6-Tetrafluoropyridyl)sulfoximines: synthesis, X-ray crystallography, and halogen bonding
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DOI: 10.1039/d0qo01139h
Abstract: N-(Tetrafluoropyridyl)sulfoximines are obtained from NH-sulfoximines and pentafluoropyridine under solution-based or mechanochemical conditions, and the solid-state structures of 26 products have been determined by X-ray diffraction analysis. read more here.
Keywords: tetrafluoropyridyl sulfoximines; crystallography halogen; ray crystallography; synthesis ray ... See more keywords
Synthesis, X-ray structure and magnetic properties of the apically functionalized monocapped cobalt(II) tris-pyridineoximates possessing SMM behaviour.
Sign Up to like & getrecommendations! Published in 2023 at "Dalton transactions"
DOI: 10.1039/d2dt04073e
Abstract: The title cobalt(II) pseudoclathrochelate complexes possess an intermediate trigonal prismatic-trigonal antiprismatic geometry. As follows from PPMS data, they exhibit an SMM behaviour with Orbach relaxation barriers of approximately 90 K. Paramagnetic NMR experiments confirmed a… read more here.
Keywords: magnetic properties; structure magnetic; synthesis ray; smm behaviour ... See more keywords
Synthesis, X-ray structures, and magnetic properties of seven polynuclear Cu(II) complexes containing pyrazole-3,5-dicarboxylate with various ancillary ligands
Sign Up to like & getrecommendations! Published in 2023 at "New Journal of Chemistry"
DOI: 10.1039/d3nj00821e
Abstract: A series of polynuclear Cu(II) complexes, namely, (Him)2[Cu2(pzdc)2(H2O)2] (1), [Cu3(pzdc)2(im)2(H2O)4] (2), {[Na4Cu4(pzdc)4(im)4(H2O)2]·16H2O}n (3), (Hamp)2[Cu2(pzdc)2(H2O)2] (4), (H2tmdp)2[Cu4(pzdc)4(H2O)2]·2H2O (5), {[Cu2(pzdc)2][Cu(H2O)6]}n (6), and [Cu3(pzdc)2(en)2(H2O)2]n (7) were successfully synthesized under the reaction of Cu(NO3)2∙3H2O,... read more here.
Keywords: pzdc h2o; synthesis ray; cu2 pzdc; pzdc ... See more keywords
Synthesis and X-ray crystallography of new N-, O-acyl pseudoephedrines
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DOI: 10.1080/00397911.2023.2207127
Abstract: Abstract N-acylation and O-acylation of pseudoephedrine are studied by using aroyl chlorides and/or ethyl chloroformate as acylating agents. Thus, treatment of pseudoephedrine or its salt with benzoyl or p-nitrobenzoyl chlorides affords the corresponding N- or… read more here.
Keywords: synthesis ray; new acyl; acyl pseudoephedrines; ray crystallography ... See more keywords
Synthesis, X-ray structure, in vitro HIV and kinesin Eg5 inhibition activities of new arene ruthenium complexes of pyrimidine analogs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2017.1334259
Abstract: Abstract Three new ruthenium(II)-arene complexes of the general formula [{(η6-p-cymene)Ru(L)}2](Cl)2), where L are monastrol (L1), ethyl 4-(3-hydroxyphenyl)-6-methyl-2-thioxo-pyrimidine-5-carboxylate (L2) or its 4-bromophenyl analog (L3), have been synthesized and characterized by elemental analysis, 1H, 13C, and 2-D… read more here.
Keywords: kinesin eg5; ruthenium; hiv; synthesis ray ... See more keywords