Light-Promoted Ni-Catalyzed Cross-Coupling of Aryl Chlorides with Hydrazides: Application to the Synthesis of Rizatriptan.
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DOI: 10.1021/acs.orglett.3c01047
Abstract: A general and highly efficient photochemical C-N coupling reaction of challenging (hetero)aryl chlorides with hydrazides is reported. Catalyzed by a Ni(II)-bipyridine complex, this reaction provides an efficient tool for the synthesis of arylhydrazines in the… read more here.
Keywords: chlorides hydrazides; synthesis rizatriptan; light promoted; synthesis ... See more keywords