Enantioselective Total Synthesis of (+)-Sieboldine A and Analogues Thereof.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c02737
Abstract: An 11-step enantioselective total synthesis of (+)-sieboldine A (1) has been accomplished from (5R)-methylcyclohex-2-en-1-one (16), in which an intramolecular ketone/ester reductive coupling followed by one-pot acidic treatment to quickly construct the unique oxa-spiroacetal and a… read more here.
Keywords: total synthesis; sieboldine analogues; synthesis sieboldine; enantioselective total ... See more keywords