Convenient synthesis of spiroindolenines from tryptamine-derived isocyanides and organic azides by cobalt catalysis in pure water
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DOI: 10.1039/d1gc00270h
Abstract: A Co-catalyzed coupling of 3-(2-isocyanoethyl)indoles with organic azides in pure water for accessing spiroindolenine derivatives was developed. This strategy features mild reaction conditions, high atom-economy, excellent yields, wide substrate scopes, and broad functional group tolerance.… read more here.
Keywords: pure water; organic azides; synthesis spiroindolenines; convenient synthesis ... See more keywords