Biotransformation Enables Innovations toward Green Synthesis of Steroidal Pharmaceuticals.
Sign Up to like & getrecommendations! Published in 2022 at "ChemSusChem"
DOI: 10.1002/cssc.202102399
Abstract: Steroids have been widely used in birth-control, prevention and treatment of various diseases, representing the largest sector after antibiotics in the global pharmaceutical market. The steroidal active pharmaceutical ingredients (APIs) have been produced via partial… read more here.
Keywords: production; biotransformation enables; synthesis steroidal; steroidal ... See more keywords
Biological synthesis of ZnO nanoparticles using C. albicans and studying their catalytic performance in the synthesis of steroidal pyrazolines
Sign Up to like & getrecommendations! Published in 2017 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2013.05.004
Abstract: Abstract In this study, we describe a green and simple procedure for biosynthesis of ZnO nanoparticles using Candida albicans as eco-friendly reducing and capping agent. The synthesized ZnO nanoparticles were characterized by UV–vis spectroscopy, powder… read more here.
Keywords: microscopy; nanoparticles using; synthesis steroidal; zno nanoparticles ... See more keywords
Synthesis of steroidal imidazolidinthiones as potential apoptotic agents: Investigation by theoretical and experimental studies.
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DOI: 10.1016/j.bioorg.2018.04.029
Abstract: New steroidal imidazolidinthione derivatives (4-6) were synthesized from steroidal thiosemicarbazones and dichloroethane. The synthesized compounds were characterized using spectral data analysis. Theoretical DFT involving B3LYP/6-31G∗∗ level of theory was employed to gain insights into the… read more here.
Keywords: steroidal imidazolidinthiones; potential apoptotic; agents investigation; imidazolidinthiones potential ... See more keywords
Synthesis of some steroidal mitocans of nanomolar cytotoxicity acting by apoptosis.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2020.112425
Abstract: Several steroids (abiraterone, prednisone, testosterone, cholesterol) and the BCL-2 inhibitor bexarotene were used as starting materials to synthesize iperazinyl-spacered rhodamine B conjugates. The conjugates were screened for their cytotoxicity in SRB assays against several human… read more here.
Keywords: cytotoxicity acting; mitocans nanomolar; steroidal mitocans; synthesis steroidal ... See more keywords
Synthesis of steroidal molecular compasses: exploration of the controlled assembly of solid organic materials
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DOI: 10.1039/c7ce00157f
Abstract: In this work, five steroid-flanked derivatives of p-nitroaniline were studied to assess the influence of these rigid, chiral frameworks on the solid-state patterning of a dipolar dye, striving to drive the self-assembly of noncentrosymmetric crystals,… read more here.
Keywords: molecular compasses; organic materials; optics; steroidal molecular ... See more keywords