Mechanochemical synthesis of N-tert-butanesulfinyl imines under metal-free conditions
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DOI: 10.1016/j.tet.2017.11.028
Abstract: A simple and convenient mechanochemical method for the condensation of aldehydes with tert-butanesulfinamide using catalytic amounts of iodine under metal- and solvent-free conditions is described. read more here.
Keywords: free conditions; imines metal; butanesulfinyl imines; mechanochemical synthesis ... See more keywords
Efficient synthesis of (2S)-tert-butyl 2-(2-bromopropanamido)-5-oxo-5-(tritylamino)pentanoate as a precursor of PET radiotracer [18F]FPGLN
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DOI: 10.1080/00397911.2017.1315671
Abstract: ABSTRACT This study describes a convenient protocol for the synthesis of (2S)-tert-butyl 2-(2-bromopropanamido)-5-oxo-5-(tritylamino)pentanoate, which can serve as an appropriate precursor of (2S)-5-amino-2-(2-[18F]fluoropropanamido)-5-oxopentanoic acid (N-(2-[18F]fluoropropionyl)-L-glutamine, [18F]FPGLN) for tumor positron emission tomography imaging. Five-step synthesis starting from… read more here.
Keywords: butyl bromopropanamido; tert butyl; precursor; 18f fpgln ... See more keywords