Concise Synthesis of Tetrazole Macrocycle
Sign Up to like & getrecommendations! Published in 2017 at "Organic Letters"
DOI: 10.1021/acs.orglett.7b02319
Abstract: A concise two step synthesis of tetrazole containing macrocycles from readily accessible starting materials is presented. The first step comprises a chemoselective amidation of amino acid derived isocyanocarboxylicacid esters with unprotected symmetrical diamines to afford… read more here.
Keywords: concise synthesis; tetrazole macrocycle; synthesis tetrazole; synthesis ... See more keywords
Asymmetric synthesis of tetrazole and dihydroisoquinoline derivatives by isocyanide-based multicomponent reactions
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DOI: 10.1038/s41467-019-09904-5
Abstract: Although isocyanide-based multicomponent reactions were proven to be simple, elegant and facile strategies for the synthesis of highly valuable nitrogen-containing heterocycles, their asymmetric versions accessing to optically active nitrogen heterocyclic compounds are rather limited. Here,… read more here.
Keywords: multicomponent reactions; synthesis tetrazole; reaction; asymmetric synthesis ... See more keywords