Synthesis of a Thiazole Library via an Iridium-Catalyzed Sulfur Ylide Insertion Reaction
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DOI: 10.1021/acs.orglett.2c02996
Abstract: A library of thiazoles and selenothiazoles were synthesized via Ir-catalyzed ylide insertion chemistry. This process is a functional group, particularly heterocycle-substituent tolerant. This was applied to the synthesis of fanetizole, an anti-inflammatory drug, and a… read more here.
Keywords: ylide insertion; synthesis thiazole; thiazole library; insertion ... See more keywords
Synthesis of Thiazole Linked Imidazo[2,1-b]Thiazoles as Anticancer Agents
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DOI: 10.1080/10406638.2019.1689514
Abstract: Abstract Based on the search for new heterocyclic drugs suitable as anticancer agents and our knowledge of the efficacy of thiazol and imidazothiazole derivatives as anticancer drugs, we have created four new series of thiazolylimidazothiazole… read more here.
Keywords: anticancer agents; thiazoles anticancer; linked imidazo; synthesis thiazole ... See more keywords