Synthesis of thienopyrimidine derivatives as inhibitors of STAT3 activation induced by IL-6.
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DOI: 10.4014/jmb.1811.11046
Abstract: A series of thienopyrimidine compounds (6Aa-g and 6Ba-d) were synthesized and characterized by NMR spectroscopy and mass spectrometry. These compounds (6Aa-g and 6Ba-d) potently inhibited STAT3 expression induced by IL-6 in a dose-dependent manner with… read more here.
Keywords: thienopyrimidine; synthesis thienopyrimidine; derivatives inhibitors; inhibitors stat3 ... See more keywords