An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds
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DOI: 10.1002/open.202100268
Abstract: Abstract An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields.… read more here.
Keywords: hydrazones synthesis; way generate; electrochemical way; generate amphiphiles ... See more keywords
Synthesis of 1,2,3-Triazole Derivatives from 2,3-Dienoates of Methyl Maleopimarate
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DOI: 10.1007/s10600-017-1984-5
Abstract: Hybrid compounds based on N-maleopimarimides containing a triazole-ring pharmacophore were prepared via 1,3-dipolar cycloaddition of methyl-2-azidoacetate to allenoates. read more here.
Keywords: triazole derivatives; derivatives dienoates; synthesis triazole; dienoates methyl ... See more keywords
Facile synthesis of 1,2,3-triazole-fused indolo- and pyrrolo[1,4]diazepines, DNA-binding and evaluation of their anticancer activity.
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DOI: 10.1016/j.bioorg.2019.103306
Abstract: A facile synthetic strategy has been developed for the generation of structurally diverse N-fused heterocycles. The formation of fused 1,2,3-triazole indolo and pyrrolodiazepines proceeds through an initial Knoevenagel condensation followed by intramolecular azide-alkyne cycloaddition reaction… read more here.
Keywords: fused indolo; facile synthesis; triazole fused; synthesis triazole ... See more keywords
Synthesis of Triazole-Fused Phenanthridines through Pd-Catalyzed Intramolecular Phenyl C–H Activation of 1,5-Diaryl-1,2,3-triazoles
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DOI: 10.1055/s-0037-1611859
Abstract: An efficient method for the synthesis of triazole-fused phenanthridines from 1,5-diaryl-1,2,3-triazoles under palladium catalysis has been developed. The reaction proceeds through Pd-catalyzed intramolecular phenyl C–H activation of 1,5-diaryl-1,2,3-triazoles. This method provides a concise and efficient… read more here.
Keywords: fused phenanthridines; synthesis triazole; intramolecular phenyl; catalyzed intramolecular ... See more keywords
Synthesis of 1,2,3-triazole-substituted 6,7-dihydroindolizin-8(5H)-one derivatives mediated by Selectfluor
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DOI: 10.1177/1747519819857478
Abstract: The 1,2,3-triazole and 1H-1,2,3-benzotriazole-substituted 6,7-dihydroindolizin-8(5H)-one derivatives were synthesized by the reaction of (E)-7-(arylmethylidene)-6,7-dihydroindolizin-8(5H)-ones with 1,2,3-triazole and 1H-1,2,3-benzotriazole in the presence of Selectfluor in moderate yield. The structures of all the products were characterized thoroughly by… read more here.
Keywords: dihydroindolizin one; triazole substituted; one derivatives; derivatives mediated ... See more keywords